This data was submitted by Tom Palmer ( palmer@ncsc.org ) Enjoy - Terry --- Terry Myerson International AVS Center North Carolina Supercomputing Center tvv@ncsc.org ----------------------------------- DESCRIPTION Multichannel cardiac mapping systems are used to acquire, analyze, and display electrical data sensed by electrodes placed directly on or within the heart tissue. The electrodes measure the potentials generated by biological electrical sources within the heart tissue and those due to externally applied electrical fields from defibrillators and pacemakers. The cardiac potentials are analyzed to determine the approximate times that activation wavefronts passed beneath or near the electrode. After a study, the heart of the experimental animal (in this case, a dog) is removed and fixed in formalin. The acquisition of anatomic information is then carried out using MRI. The information gathered as described is used to compute secondary variables, interpolate values of sparsely measured variables, and display the results. The data are traditionally displayed as contour lines superimposed on stylized or individualized cardiac contours. However, the volumetric nature of the data, and the need to view multiple variables simultaneously, lead to attempts to use multivariate volume visualization techniques to display the data. This dataset was the impetus for the development of the language-based multivariate classification and shading techniques described in: T.C. Palmer, E.V. Simpson, K.M. Kavanagh, and W.M. Smith. "Visualization of Bioelectric Phenomena". In "High Performance Computing in Biomedical Research". CRC Press, October 1992. DATA The dataset actually consists of five separate (but registered) volumes. All volumes are 128x128x128 with one byte per voxel. Z varies fastest. Splice them together as required. act.raw Activation time (time at which the wavefront passed this point). pot.raw Defibrillation shock potential pot-mag.raw Defibrillation shock potential gradient magnitude valid.raw Valid data region (since the bioelectric data is only acquired or interpolated for voxels inside the myocardium). Encoding: undefined: 0 boundary: 128 defined: 255 mri.raw MRI scan of canine heart EXPERIMENTS Try extracting isosurfaces of activation to display in conjunction with MRI surfaces. This yields an "isochrone" - a visual depiction of the wavefront. We've colored these surfaces by several variables including conduction velocity. Since the gradient of the activation data represents the change in time with respect to distance, 1/|gradient| serves as an approximation of conduction velocity. Other things to try: Coloring isochrones by shock potential gradient magnitude. Coloring the MRI surface by shock potential. CREDITS The MR dataset was acquired in the microscopic MRI laboratory of G. Allan Johnson with technical assistance by Sharon Melnick (Duke University). The bioelectric data was acquired by Katherine Kavanagh (University of Alberta). Interpolation and registration were performed by Ed Simpson (Duke). Visualization work was done by Tom Palmer (Cray Research), Ed Simpson, and Bill Smith (Duke). CONTACT Tom Palmer (919) 248-1117 Cray Research, Inc. palmer@ncsc.org North Carolina Supercomputing Center PO BOX 12889 RTP, NC 27709